Before you get married to that handsome man or lovely lady you admire, you should really consider going for a genotype test so the answer is NO. A depressed and painful existence would be spared if you did this. The genetic make-up of a particular creature is its genotype, and this definition sums it up nicely. AA, AS, AC, and SS are the four most common genotypes in the world.
The importance of a genotype test before.
In order to avoid sickle cell illness, all couples planning to wed should have their genotypes tested prior to their weddings. Sickle cell disease is a devastating medical ailment that affects a large percentage of the world’s population, but is most prevalent in Africa because it is a recessive genetic disorder. The fear of having children with sickle cell disease should be enough to motivate people to take action.
What happens when you say “I do” without a genotype test?
If a man and a woman do not take this genotype test before they say “I do,” they are more likely to have children with sickle cell disease. As a result, both the child and the parents are likely to live a life of misery, agony, and regret.
Study this table below carefully:
AA + AA = AA, AA, AA, AA (Excellent)
AA + AS = AA, AS, AA, AS, (Good)
AA + SS = AS, AS, AS, AS, (Fair)
AA + AC = AA, AA, AA, AC. (Good)
AS + AS = AA, AS, AS, SS, (Very Bad)
AS + SS = AS, SS, SS, SS, (Very Bad)
AS + AC = AA, AC, AS,SS. (Bad; Advice needed)
SS + SS = SS, SS, SS, SS, (Very Bad)
AC + SS = AS, AS, SS, SS, (Very Bad)
AC + AC = AA, AC, AC, SS. ( Bad; Advice needed)
Risk involved in getting married without a genotype test.
There are dangers in getting hitched without first getting a genetic or genotype test.
1. The disease known as sickle cell anemia.
When both parents are AS, there is a 25% chance that they will have a child with sickle cell genotype. This is not widely known. Each pregnancy is a one-time experience, and the likelihood of having a sickle cell kid does not decrease with subsequent pregnancies, according to this statistic. One in four pregnancies produce a child with this condition.
Having sickle cell disease is a long-term condition that affects the entire body. There is a wide range of severity in the condition. People with SCD now have a 40–60 year life expectancy in high-income nations because to improvements in SCD diagnosis and treatment. Life expectancy for children born with SCD in low-income nations is only 23 years.
For the rest of their lives, patients with SCD can expect to go in and out of the hospital due to the unpredictable and excruciating pain that they experience. People with SCD may experience long-term damage to their spleen and other internal organs as well as their joints, bones, eyes, liver, heart, and kidneys.
What is the most compatible Genotype for marriage?
AA and AA genotypes are the most compatible for marriage. If an AA marries an AA, it’s the best match. That way, you don’t have to worry about your future children’s genetic compatibility. It’s important to remember that you’ll have children as a result of your marriage.
The Bottom Line.
•Your ability to develop and sustain a happy, healthy marriage includes a compatible genetic component. If you want to be on the safe side, you should take a pre-marital and genotype test. But there is nothing wrong with not having children with your partner, if you both love and cherish each other.
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